| Keywords |
| buy winstrol, winstrol depot, winstrol tablets, Cutting Steroids, Equipoise, Masteron, Primobol, Primobolan Depot, Trenabol, anabolic steroids, buy steroids, online, best steroids, steroid, pharmacy, legal steroid, sale steroid, steroid for sale, cheapest steroids, steroid cycles, anabol,steroide anabolisant, anabolika, anabole steroide, danabol, anabolica, steroides, deca, durabolin, sustanon |
|
|
nandrolone
Nandrolone drug is unique in that 5a -reductase, the enzyme which converts testosterone to the more-potent DHT, actually converts Nandrolone to a less-potent compound. Therefore this AAS is somewhat deactivated in the skin, scalp, and prostate, and these tissues experience an effectively-lower androgen level than the rest of the body. Therefore, for the same amount of activity as another drug at the androgen receptors (ARs) in muscle tissue, Deca gives less activity in the scalp, skin, and prostate. Thus, it is the best choice for those particularly concerned with these things.
Its effectiveness at the androgen receptor of muscle tissue is superior to that of testosterone: it binds better. Yet, it gives only about half the muscle-building results per milligram. This I think is a result of its being less effective or entirely ineffective in non-AR-mediated mechanisms for muscle growth.
It also appears less effective or entirely ineffective in activity on nerve cells, certainly on the nerve cells responsible for erectile function. Use of Deca as the sole AAS often results in complete inability to perform sexually.
These problems can be solved by combining with a drug that does supply the missing activity: e.g. testosterone.
Nandrolone is proven to be a progestin. This fact is of clear importance in bodybuilding, because while moderate Deca-only use actually lowers estrogen levels as a consequence of reducing natural testosterone levels and thus allowing the aromatase enzyme less substrate to work with, Deca nonetheless can cause gyno in some individuals. Furthermore, just as progesterone will to a point increase sex drive in women, and then often decrease it as levels get too high, high levels of progestogenic steroids can kill sex drive in male bodybuilders, though there is a great deal of individual variability as to what is too much.
Incidentally, this progestogenic activity also inhibits LH production, and contrary to common belief, even small amounts of Deca are quite inhibitory, approximately as much so as the same amount of testosterone.
To some extent, Nandrolone aromatizes to estrogen, and it does not appear that this can be entirely blocked by use of aromatase inhibitors – indeed, aromatase may not be involved at all in this process (there is no evidence in humans that such occurs) with the enzyme CYP 2C11 being in my opinion the more likely candidate for this activity. In any case, Cytadren, an aromatase inhibitor, has not been found effective in avoiding aromatization of Nandrolone.
The drug is moderately effective at doses of 400 mg/week. The long half-life of Nandrolone decanoate makes it unsuited to short alternating cycles, but suitable for more traditional cycles, with a built-in self-tapering effect in the weeks following the last injection.
Nandrolone decanoate is the chemical name of active ingredient in Deca Durabolin. Deca Durabolin is a registered trademark of Organon Corporation in the United States and/or other countries.
|
About Winstrol
Winstrol - Stanozolol is a very commonly used anabolic steroid for cutting cycles. While many people will attempt to use Dianabol or even Anadrol for cutting cycles, I´ve really never heard of anyone using Stanozolol for anything except a cutting cycle. It´s a bit of a one-trick-pony in this respect. Let me repeat that: Stanozolol is a cutting drug. Not many people will argue for its use in a bulking cycle. It´s certainly not a very effective compound for treating anemia (1) and thus, one could rightly assume that its role in bulking cycles is very limited. One novel use for Winstrol in any cycle (perhaps even bulking) would be to use it at a very limited dose, in order to lower SHBG. (2) One of the properties of Winstrol is it´s profound ability to lower SHBG much more than other steroids. A dose of .2mg/kg lowered SHBG significantly, which would in turn, raise the amount of free testosterone circulating in the body. As with 99% of steroids, however, it´s important to note that suppression of your natural hormonal levels will occur (though perhaps not to the extent that it will with many other steroids).(10) As with running virtually any compound, testosterone supplementation (i.e. running test in a cycle containing Winstrol) is warranted to avoid possible sexual dysfunction.
Winstrol & Stanozol Side Effects
Adding it to a heavy bulking cycle could be problematic, as Stanozolol is a 17aa compound, meaning that it´s been altered to endure the first pass through your liver without being destroyed. This makes it an orally active compound; so many people choose to take the pills which are available from both legitimate pharmaceutical companies as well as Underground Labs. Unfortunately, since it is 17aa, it is also liver toxic& in fact; Stanozolol has one of the worst hepatoxicity (mg for mg) of any steroid. This is the reason its addition to a bulking cycle could be problematic; generally a bulking cycle will be very heavy, dosage wise as well as toxicity-wise. It also has undesirable results on Cholesterol, and a mere 6mgs/day of Stanozolol can lower HDL by 33% and raise LDL by 29% (3). Cardiac Hypertrophy, even at lower doses could be a concern with Winstrol as well (4) Thus, many people limit their intake of Stanozolol to precontest or Summer-cutting types of cycles. It´s generally accepted that due to the toxicity issues of Stanozolol, its use should be limited to 6 weeks& as with anything though, many people have run it for up to 12 weeks with no problems.
As it is available in both an oral form as well as an injectable form, and both contain the same compound, you might find this next part odd, but the injectable route actually produces greater nitrogen retention. (5) Another counterintuitive fact about Winstrol is that although the anabolic rating of this product is very high, not too many people report much weight gain off of it. Also, it has a very weak Androgen Receptor binding ability (6), which is kind of odd for a drug with Winstrol’s effects. unusual for a “cutting” steroid. Protein synthesis is reasonably high with Winstrol (7), although weight gain is low, paradoxically.
In all, this is a very odd compound, from a chemical/biological point of view. My personal experience with it was that it can be used as a cheap substitute for Anavar, although I prefer the latter. Also, the injections hurt like hell.. |
| |
|
